105001 Insigneo showcase newsletter

105001 Insigneo showcase newsletter

2022

TRAINING

PROJECT NEWS

EVENTS ROUNDUP

1

CONTENTS AND WELCOME

Contents Inside this issue

technologies and we are pleased to further develop our strategic partnerships with industrial collaborators (see Jan Wolber GE feature on page five). At a local level our Commercialisation Manager, Alex Wilkinson, has been actively engaging with members to help define pathways to commercial translational impact. Building on the theme of multi-scale computational modelling, Insigneo is bringing together researchers working on cutting-edge biomedical imaging and smart sensing technologies for the understanding of living systems from the molecule through to the patient. Integrating these images and signals with modelling and simulation gives an augmented understanding of the basic biology and disease pathophysiology at the cell, organ, patient and population level. We are particularly pleased with the interest in Insigneo from colleagues working in the faculty of science at this interface of physical and biomedical science. With our new research theme structure, we have assembled a collection of dynamic researchers across the University of Sheffield, the University of Sheffield’s Advanced Manufacturing Research Centre (AMRC), the Sheffield Teaching Hospital and the Sheffield Children’s Hospital directing these interlocking themes in our new, expanded research director structure which features early career scientists and clinical pioneers of Insigneo technologies (see theme diagram page four).

2

Introduction

4

Insigneo research themes Partnerships and placements

5

6

Clinical translation

6

12

8

Insigneo timeline

10

Updates from our research themes

13

Events

Insigneo Organisational Structure

14

Training

Thanks to the efforts of all the members and the continued support of our stakeholders over these last ten years the future for Insigneo and in silico medicine is bright. Hope to see you at the 10th anniversary showcase.

15

Summer research

14

programme 13

Welcome

Jim Wild & Damien Lacroix

Insigneo Executive Director - Professor Jim Wild

Welcome from Jim Wild & Damien Lacroix who were formally appointed to their new roles in 2021.

(Department of Infection, Immunity and Cardiovascular Disease)

Having been members of Insigneo since its inception we have seen the institute grow and evolve to meet the cross-disciplinary research challenges that medical technology and basic science can help address in a modern healthcare setting. Ten years ago, the focus of the institute was very much driven by the excellent work of the founders establishing the field of research of the virtual physiological human (VPH) in collaboration with modellers, experimentalists and clinicians, and where patient- specific modelling was developed to understand disease processes and predict outcomes. In the last ten years, the institute has actively worked with the VPH Institute and the Avicenna Alliance to see the concept of in silico clinical trials being adopted by regulatory bodies as a means of faster introduction and more effective validation of devices and interventions;

we are proud to say that Insigneo has been at the forefront of this endeavour.

arrived in a healthcare setting with a significant push from industry. We are combining our patient-specific physics- based modelling approach with >Page 1 Page 2-3 Page 4-5 Page 6-7 Page 8-9 Page 10-11 Page 12-13 Page 14-15 Page 16

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