Research Report 2019_20

Research Report 2019_20

2019-20 Research Report 1 2019-2020 Research Report

601 Genome Way Huntsville AL 35806

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Introduction ............................................................................ 4

Foundational Genomics . ....................................................... 6 Greg Barsh, MD, PhD and lab. ............................................................. 8 Thomas May, PhD and lab ............................................................. 10 Human Health Research ..................................................... 12 Richard Myers, PhD and lab............................................................... 14 Sara Cooper, PhD and lab. ................................................................. 16 Devin Absher, PhD and lab................................................................. 18 Greg Cooper, PhD and lab.................................................................. 20 David Bick, MD and The Smith Family Clinic for Genomic Medicine... 22 Elaine Lyon, PhD and the HudsonAlpha Clinical Services Lab. ....... 24 Agriscience Research . ........................................................ 26 Jane Grimwood, PhD, Jeremy Schmutz and the HGSC. .................... 28 Kankshita Swaminathan, PhD and lab............................................... 30 Josh Clevenger, PhD and lab. ............................................................ 34 Alex Harkess, PhD and lab ............................................................ 36 Supporting the Institute ...................................................... 38 The HudsonAlpha Health Alliance .................................................. 40 Jian Han, MD, PhD and public and private collaboration ................ 42 COVID-19 and the HudsonAlpha campus innovators response . ...... 44 Neil Lamb, PhD and Educational Outreach .................................... 46 Shawn Levy, PhD and HudsonAlpha Discovery................................... 52

HudsonAlpha Faculty .......................................................... 54

References . .......................................................................... 63

Adjunct Faculty and Scientific Advisory Board . ............... 64

HudsonAlpha 2019-2020 in Review ................................... 66

Discovery, education, and

Thirty years ago, the Human Genome Project marked a new era in science exemplified by the power of collaboration for a common goal, and the importance of communication and open sharing of >Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 Page 10 Page 11 Page 12 Page 13 Page 14 Page 15 Page 16 Page 17 Page 18 Page 19 Page 20 Page 21 Page 22 Page 23 Page 24 Page 25 Page 26 Page 27 Page 28 Page 29 Page 30 Page 31 Page 32 Page 33 Page 34 Page 35 Page 36 Page 37 Page 38 Page 39 Page 40 Page 41 Page 42 Page 43 Page 44 Page 45 Page 46 Page 47 Page 48 Page 49 Page 50 Page 51 Page 52 Page 53 Page 54 Page 55 Page 56 Page 57 Page 58 Page 59 Page 60 Page 61 Page 62 Page 63 Page 64 Page 65 Page 66 Page 67 Page 68

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