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Vital Highlights 2014-2021

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Vital Highlights 2014-2021

V I TAL H I GHL I GHTS 20 1 4 - 202 1

Acknowledgment of Country

Sydney Vital acknowledges the Traditional Custodians of the lands on which our research centre has been bui lt , the Gaimariagal , Guringai and Dharug peoples , and we honour and pay our respects to their ancestors . We acknowledge and pay our respects to al l Aboriginal and Torres Strait Islander peoples and to Elders past , present and emerging . We acknowledge that past , current and future Aboriginal and Torres Strait Islander peoples are the continuing custodians of this country upon which we l ive , work and meet and that it is from their blood , courage , pride and dignity that we are able to continue to l ive , work and meet on this ancient and sacred country .

Sydney Vital would l ike to acknowledge the support of our pr incipal funding organisations : the New South Wales Government through the Cancer Institute NSW , the University of Sydney and the Northern Sydney LHD .

Sydney Vital Translational Cancer Research Centre

Level 8 , Kol l ing Bui lding Royal North Shore Hospital St Leonards , NSW , 2065

E : sydneyvital . admin @ sydney . edu . au P : ( 02 ) 9926 4726 W : www . sydneyvital . org . au

This work is copyr ight . It may be reproduced in whole or part for internal or training purposes , subject to the inclusion of acknowledgement of the source . It may not be reproduced for commercial usage or sale . Reproduction for purposes other than those indicated above requi res wr itten permission from Sydney Vital .

TABLE OF CONTENTS TABLE OF CONTENTS

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A W O R D F R O M O U R D I R E C T O R

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A W O R D F R O M O U R D I R E C T O R

I N T R O T O T H E T C R C

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I N T R O T O T H E T C R C

A B O U T S Y D N E Y V I T A L

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A B O U T S Y D N E Y V I T A L

E X E C U T I V E T E A M

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E X E C U T I V E T E A M

R E S E A R C H

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R E S E A R C H

F L A G S H I P S

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F L A G S H I P S

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F O R M E R F E L L O W S , W H E R E A R E T H E Y N O W ?

T R A N S L A T I O N A L C E N T R E S O F E X C E L L E N C E

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T R A N S L A T I O N A L C E N T R E S O F E X C E L L E N C E

A W A R D E E S

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A W A R D E E S

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F U N D I N G A L L O C A T I O N 2 0 1 4 - 2 0 2 0

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V I T A L F E E D B A C K

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N S W P R E M I E R ' S A W A R D S

R E S E A R C H I N F R A S T R U C T U R E

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R E S E A R C H I N F R A S T R U C T U R E

M E M B E R S H I P

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M E M B E R S H I P

O U T P U T S & A C H I E V E M E N T S

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O U T P U T S & A C H I E V E M E N T S

H O W S Y D N E Y V I T A L I S M A K I N G A D I F F E R E N C E

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H O W S Y D N E Y V I T A L I S M A K I N G A D I F F E R E N C E

O U R C O M M U N I C A T I O N S T R A T E G Y

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A WORD FROM OUR DI RECTOR

Professor Dale Bailey

Director , Sydney Vital Flagship Lead , Translational Theranostics

Sydney its seventh year of operation as a fully - fledged Translational Cancer Research Centre . Along the way priorities have shifted where necessary and research activities modified , however , our focus has remained on patient - centred translational cancer research . Vital is now entering “ Translational ” means that we try to take concepts that look promising and take them into practice in the clinic or to fill a void in patient care . Our ultimate measure of success is the outcome for cancer patients in New South Wales . It is therefore pleasing , though not yet satisfactory , to see in the latest national cancer statistics that patients with cancer in the Northern Sydney Local Health District have some of the best outcomes in Australia . There is no one single reason for this , yet , having an environment where patient management is discussed regularly by a multi - disciplinary team of clinicians and researchers with a strong research focus is part of the formula . At Sydney Vital we aim to turbo - charge existing activities in our region in cancer research , train the next generation of clinicians / researchers , create opportunities to better inform our community about the latest advances in cancer care , and serve as a stepping stone to launch junior clinicians and researchers into the next phase of their careers .

Over our seven years we have been able to support in excess of 130 clinicians and researchers , many of whom have gone on to develop their own careers based on their research experience supported by Sydney Vital . One of last year ’ s research fellows , Dr David Chan , was successful at his first attempt in securing a five year NHMRC Investigator Award which will allow him to continue the research that he started with Sydney Vital . The first half of 2020 is a time like no other for the majority of us . I am pleased to be able to report that the research activities of Sydney Vital have been able to continue due to the passion and commitment that our researchers and professional staff possess . “ Social distancing ” has not meant that successes have become more distant . Our current programme grant has less than a year to run and we are yet to find out whether our program will be renewed by CINSW and the University of Sydney from July 2021 . We are all anticipating a different future and a “ new normal ” when we finally reach the other side of the COVID - 19 pandemic . Hopefully , this will be a brave new world , but no matter what form that takes we know that Sydney vital has made a tangible contribution to the current and future generation of cancer clinicians and researchers .

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INTRO TO THE TCRC In 2011 , Cancer Institute NSW introduced a translational cancer research program to bring together research , clinical training , education and service delivery within a formal framework to connect leading research and clinical institutions . Seven TCRCs were established to represent the seven Local Health Districts , in collaboration with partnering universities and teaching hospitals . These 7 TCRCs are Sydney Vital , Sydney West , Sydney Catalyst , CONCERT , Kids Cancer Alliance , TCRN , and Hunter Cancer Research Alliance .

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THE TRANSLAT IONAL RESEARCH P I PEL INE

Basic Research

TRANSLATION From basic science to human studies

Clinical Research

TRANSLATION Of new knowledge into clinical practice

Improved Health

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Sydney Vital is a Translational Cancer Research Centre based on the Royal North Shore Campus . Our aim is to take research from the laboratory bench and put this into practice . By doing so , we are able to provide patients with access to the latest medical discoveries and improve both their care and outcomes . We are funded by the Cancer Institute NSW and the University of Sydney , and our research partners include The University of Sydney , Macquarie University & Medical School , The Kolling Institute , The University of Technology Sydney , Royal North Shore Hospital , Mater Hospital , and North Shore Private Hospital .

We bring together over 500 cancer researchers who share Sydney Vital ’ s goal to ensure that the latest advances in cancer prevention , treatments and care are available to patients in the shortest time possible . We also coordinate and build research facilities that facilitate the translating of cancer research from the laboratories into routine patient care and improve treatment guidelines . Raising awareness of cancer research and gaining the community ’ s support is a vital component in a holistic community approach to cancer management . This is especially true when there were 126 , 000 new cancer cases diagnosed in Australia in 2015 and the number is predicted to rise to 150 , 000 by 2020 ( Cancer Australia 2016 ). We raise awareness of cancer research and research findings to our local community via email , newsletters , Facebook , Twitter , YouTube and we regularly update our website with the latest news and events . We run regular ‘ cancer events ’ to disseminate cancer research findings and to engage with the local community .

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EXECUT I VE TEAM

Prof Fran Boyle AM

Prof Dale Bailey Centre Director Sydney Vital ( 2019 - present ) Medical physicist

Prof Anthony Gill AM

Surgical pathologist

Medical oncologist

Prof Melanie Lovell

A / Prof Thomas Eade

Palliative medicine physician

Radiation oncologist

Prof Alexander Engel Founding Director

Sydney Vital ( 2013 - 2019 )

Dr Trisha Dwight

Prof Mark Molloy Molecular scientist

Colorectal surgeon

Cancer biologist

Founding Director NTCRU ( 2011 - 2013 ) Prof Stephen Clarke OAM

Dr Connie Diakos Medical oncologist