HudsonAlpha ED Guidebook 2021_22

HudsonAlpha ED Guidebook 2021_22

2021-2022 GUIDEBOOK CONTENTS

About HudsonAlpha Institute for Biotechnology . ...............................2–3 HudsonAlpha Blogs & Podcasts ...............................................................4 Life Science Educator Resources .............................................................5 Executive Summary ..................................................................................6 Science Snapshots ....................................................................................7 New Findings . .....................................................................................8–17

Recent research findings provide a quick update on the genetics, genomics, and biotechnology field. This section represents discoveries, treatments or applications that have been announced during the past year.

Infographic on Genomics-Driven Oncology .....................................18–19 HudsonAlpha Digital Applications .........................................................20 Snapshot References & Image Credits ..................................................21

ONLINE BIOTECH BASICS

Looking for a place to start? HudsonAlpha offers easy-to-understand explanations of foundational concepts at hudsonalpha.org/biotech-basics. Twenty-four key technologies or concepts are described in detail.

Language and concepts are intentionally geared to a high school or public audience.

science for life ®

About HudsonAlpha The HudsonAlpha Institute for Biotechnology is a nonprofit institute dedicated to developing and applying scientific advances to health, agriculture, learning and commercialization. Opened in 2008, HudsonAlpha’s vision is to leverage the synergy between discovery, education, medicine and economic development in genomic sciences to improve the human condition around the globe. The HudsonAlpha biotechnology campus consists of 152 acres nestled within Cummings Research Park, the nation’s second largest research park. The state-of-the-art facilities co-locate nonprofit scientific researchers with entrepreneurs and educators. HudsonAlpha has become a national and international leader in genetics and genomics research and biotech education. It includes more than 45 diverse biotech companies on campus.

HudsonAlpha scientists are adding to the world’s body of knowledge about the basis of life, health, disease and biodiversity and seeking to enable:

Genomic Research

● Earlier and/or less invasive diagnostics ● Better, more customized treatments for disease ● Improved food, fiber and energy sources

Significant Research Publications Our research- ers have been published in more than 900 scientific publications since the beginning of HudsonAlpha in 2008 to help secure a global leadership position in genomic research.

Current research focus areas are:

Foundational Research

Plant Science and Sustainable Agriculture Applying genomic knowledge to agriculture and bioenergy to create a more sustainable world

Genomic Health Leveraging the power of the human genome to diagnose, predict and prevent disease as well as helping others incorporate genomics into practice

Research that improves the under- standing of biological phenomena. Includes studies of natural variation, principles of bioethics, and computa- tional biology and bioinformatics

Human Health

Neurological and Psychiatric Disorders Including Alzheimer disease, Parkinson disease, ALS, Huntington disease, bipolar disorder, schizophrenia, autism and epilepsy

Rare disease Undiagnosed childhood genetic disorders

Cancer Multiple forms of cancer, including breast, ovarian, prostate, kidney, brain, colon and pancreatic

Immunogenomics Application of genomic technology to understand the immune system’s role in health and disease

Autoimmune diseases Including lupus, rheumatoid arthritis, and other complex autoimmune diseases.

Global Footprint of Research Partnerships

HudsonAlpha partners with other research institutes and life sciences companies around the globe – and even in space – to make genomic discoveries.

Government support comes from: National Science Foundation U.S. Department of Energy Joint Genome Institute U.S. Department of Agriculture National Institutes of Health

National Human Genome Research Institute National Institute of Arthritis, Musculoskeletal and Skin Diseases National Heart, Lung and Brain Institute National Institute of Mental Health National Institute of Environmental Health Sciences

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Educational Outreach

HudsonAlpha’s Educational Programs HudsonAlpha's Educational Outreach team inspires and trains the next generation of life science researchers and workforce while building a more genomically-literate society. The dynamic educators at HudsonAlpha reach students, educators, medical practi- tioners, and the community through hands-on classroommodules, in-depth school and workshop experiences along with digital learning opportunities. HudsonAlpha also provides educational opportunities for healthcare providers and learning tools for patients who are making medical decisions using their personal genomic information. Additionally, the team builds genomics awareness through community outreach classes and events. Annually, these combined programs and resources reach more than 1 million individuals.

Educator Professional Learning HudsonAlpha has several opportunities for teacher professional learning, ranging from single-day workshops to ongoing classroom support. These increase an educator’s comfort in discussing genetic concepts and terminology along with the associated ethical, social and legal issues.

Student Experiences Field trips, classroom visits by industry leaders, summer camp sessions, in-depth internship opportunities and college-level laboratory courses engage students in biotechnology-related fields, increase exposure to career options, provide mentoring opportunities and equip students with a toolbox of content-specific skills.

Classroom Kits and Digital Resources HudsonAlpha has developed kits and activities to engage elementary and middle school students in hands-on experiences that match state curriculum requirements related to DNA and genetics. Multiple laboratory activities have also been crafted for students in grades 9-12. Activities highlight topics such as trait inheritance patterns, extracting DNA, exploring chromosome behavior in cells, diagnosing genetic disorders, and using bioin- formatics >Page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 Page 10 Page 11 Page 12 Page 13 Page 14 Page 15 Page 16 Page 17 Page 18 Page 19 Page 20 Page 21 Page 22 Page 23 Page 24

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